According the Museum:

St. Anthony as a hermit, surrounded by imaginative human-animal hybrids based on the model of Hieronymus Bosch.
The saint in a monk's robe kneels with a book in his hand in a hilly landscape. Besides the demonic creatures that surround him, you can see a city far in the background in the center of the picture and a burning house in the background on the right.
In the center of the picture are very small soldiers with spears on horses. A fisherman is sitting next to a pond in which a naked figure is swimming. A small, spherical figure is suspended by its legs on a hill. Another figure flies past on a flying fish.